Publications

2020

2019

  • Riera, R., Feiner-Gracia, N., Fornaguera, C., Cascante, A., Borrós, S., Albertazzi, L., 2019. Tracking the DNA complexation state of pBAE polyplexes in cells with super resolution microscopy. Nanoscale 11(38):17869-17877. https://doi.org/10.1039/C9NR02858G 
  • Pujals, S., Albertazzi, L., 2019. Super-resolution Microscopy for Nanomedicine Research. ACS Nano 13(9):9707-9712. https://doi.org/10.1021/acsnano.9b05289
  • Bastings, M.M.C., Hermans, T.M., Spiering, A.J.H., Kemps, E.W.L., Albertazzi, L., Kurisinkal, E.E., Dankers, P.Y.W., 2019. Quantifying Guest-Host Dynamics in Supramolecular Assemblies to Analyze Their Robustness. Macromol Biosci 19, e1800296. https://doi.org/10.1002/mabi.201800296
  • Post, R. a. J., van der Zwaag, D., Bet, G., Wijnands, S.P.W., Albertazzi, L., Meijer, E.W., van der Hofstad, R.W., 2019. A stochastic view on surface inhomogeneity of nanoparticles. Nat Commun 10, 1663. https://doi.org/10.1038/s41467-019-09595-y
  • Feiner-Gracia, N., Olea, R.A., Fitzner, R., El Boujnouni, N., van Asbeck, A.H., Brock, R., Albertazzi, L., 2019. Super-resolution Imaging of Structure, Molecular Composition, and Stability of Single Oligonucleotide Polyplexes. Nano Lett. 19, 2784–2792. https://doi.org/10.1021/acs.nanolett.8b04407
  • Kolpe, A., Arista-Romero, M., Schepens, B., Pujals, S., Saelens, X., Albertazzi, L., 2019. Super-resolution microscopy reveals significant impact of M2e-specific monoclonal antibodies on influenza A virus filament formation at the host cell surface. Sci Rep 9, 4450. https://doi.org/10.1038/s41598-019-41023-5 
  • Pujals, S., Feiner-Gracia, N., Delcanale, P., Voets, I., Albertazzi, L, 2019. Super-Resolution Microscopy as a Powerful Tool to Study Complex Synthetic Materials. Nat Rev Chem 2, 68–84. https://doi.org/10.1038/s41570-018-0070-2
  • Uroz, M., Garcia-Puig, A., Tekeli, I., Elosegui-Artola, A., Abenza, J.F., Marín-Llauradó, A., Pujals, S., Conte, V., Albertazzi, L., Roca-Cusachs, P., Raya, Á., Trepat, X., 2019. Traction forces at the cytokinetic ring regulate cell division and polyploidy in the migrating zebrafish epicardium. Nat Mater 18, 1015–1023. https://doi.org/10.1038/s41563-019-0381-9
  • Cremers, G.A.O., Rosier, B.J.H.M., Riera Brillas, R., Albertazzi, L., de Greef, T.F.A., 2019. Efficient Small-Scale Conjugation of DNA to Primary Antibodies for Multiplexed Cellular Targeting. Bioconjug. Chem. 30, 2384–2392. https://doi.org/10.1021/acs.bioconjchem.9b00490
  • De Coen, R., Nuhn, L., Perera, C., Arista-Romero, M., Risseeuw, M.D.P., Freyn, A., Nachbagauer, R., Albertazzi, L., Van Calenbergh, S., Spiegel, D.A., Peterson, B.R., De Geest, B.G., 2019. A synthetic rhamnose glycopolymer cell surface receptor for endogenous antibody recruitment. Biomacromolecules. https://doi.org/10.1021/acs.biomac.9b01483

2018

  • Ardizzone, A., Kurhuzenkau, S., Illa‐Tuset, S., Faraudo, J., Bondar, M., Hagan, D., Stryland, E.W.V., Painelli, A., Sissa, C., Feiner, N., Albertazzi, L., Veciana, J., Ventosa, N., 2018. Nanostructuring Lipophilic Dyes in Water Using Stable Vesicles, Quatsomes, as Scaffolds and Their Use as Probes for Bioimaging. Small 14, 1703851. https://doi.org/10.1002/smll.201703851
  • Liu, Y., Pujals, S., Stals, P.J.M., Paulöhrl, T., Presolski, S.I., Meijer, E.W., Albertazzi, L., Palmans, A.R.A., 2018. Catalytically Active Single-Chain Polymeric Nanoparticles: Exploring Their Functions in Complex Biological Media. J. Am. Chem. Soc. 140, 3423–3433. https://doi.org/10.1021/jacs.8b00122
  • Krivitsky, A., Polyak, D., Scomparin, A., Eliyahu, S., Ofek, P., Tiram, G., Kalinski, H., Avkin-Nachum, S., Feiner Gracia, N., Albertazzi, L., Satchi-Fainaro, R., 2018a. Amphiphilic poly(α)glutamate polymeric micelles for systemic administration of siRNA to tumors. Nanomedicine: Nanotechnology, Biology and Medicine 14, 303–315. https://doi.org/10.1016/j.nano.2017.10.012
  • Casellas, N.M., Pujals, S., Bochicchio, D., Pavan, G.M., Torres, T., Albertazzi, L., García-Iglesias, M., 2018. From isodesmic to highly cooperative: reverting the supramolecular polymerization mechanism in water by fine monomer design. Chem. Commun. 54, 4112–4115. https://doi.org/10.1039/C8CC01259H
  • Patiño, T., Feiner-Gracia, N., Arqué, X., Miguel-López, A., Jannasch, A., Stumpp, T., Schäffer, E., Albertazzi, L., Sánchez, S., 2018. Influence of Enzyme Quantity and Distribution on the Self-Propulsion of Non-Janus Urease-Powered Micromotors. J. Am. Chem. Soc. 140, 7896–7903. https://doi.org/10.1021/jacs.8b03460
  • van Elsland, D.M., Pujals, S., Bakkum, T., Bos, E., Oikonomeas‐Koppasis, N., Berlin, I., Neefjes, J., Meijer, A.H., Koster, A.J., Albertazzi, L., van Kasteren, S.I., 2018. Ultrastructural Imaging of Salmonella–Host Interactions Using Super‐resolution Correlative Light‐Electron Microscopy of Bioorthogonal Pathogens. Chembiochem 19, 1766–1770. https://doi.org/10.1002/cbic.201800230
  • Delcanale, P., Miret-Ontiveros, B., Arista-Romero, M., Pujals, S., Albertazzi, L., 2018. Nanoscale Mapping Functional Sites on Nanoparticles by Points Accumulation for Imaging in Nanoscale Topography (PAINT). ACS Nano 12, 7629–7637. https://doi.org/10.1021/acsnano.7b09063

2017

  • Duro‐Castano, A., Nebot, V.J., Niño‐Pariente, A., Armiñán, A., Arroyo‐Crespo, J.J., Paul, A., Feiner‐Gracia, N., Albertazzi, L., Vicent, M.J., 2017. Capturing “Extraordinary” Soft-Assembled Charge-Like Polypeptides as a Strategy for Nanocarrier Design. Advanced Materials 29, 1702888. https://doi.org/10.1002/adma.201702888
  • Labernadie, A., Kato, T., Brugués, A., Serra-Picamal, X., Derzsi, S., Arwert, E., Weston, A., González-Tarragó, V., Elosegui-Artola, A., Albertazzi, L., Alcaraz, J., Roca-Cusachs, P., Sahai, E., Trepat, X., 2017. A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion. Nat. Cell Biol. 19, 224–237. https://doi.org/10.1038/ncb3478
  • Feiner-Gracia, N., Beck, M., Pujals, S., Tosi, S., Mandal, T., Buske, C., Linden, M., Albertazzi, L., 2017b. Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona. Small 13. https://doi.org/10.1002/smll.201701631
  • Feiner-Gracia, N., Buzhor, M., Fuentes, E., Pujals, S., Amir, R.J., Albertazzi, L., 2017a. Micellar Stability in Biological Media Dictates Internalization in Living Cells. J. Am. Chem. Soc. 139, 16677–16687. https://doi.org/10.1021/jacs.7b08351
  • Oria, R., Wiegand, T., Escribano, J., Elosegui-Artola, A., Uriarte, J.J., Moreno-Pulido, C., Platzman, I., Delcanale, P., Albertazzi, L., Navajas, D., Trepat, X., García-Aznar, J.M., Cavalcanti-Adam, E.A., Roca-Cusachs, P., 2017. Force loading explains spatial sensing of ligands by cells. Nature 552, 219–224. https://doi.org/10.1038/nature24662
  • Onzen, A.H.A.M. van, Albertazzi, L., Schenning, A.P.H.J., Milroy, L.-G., Brunsveld, L., 2017. Hydrophobicity determines the fate of self-assembled fluorescent nanoparticles in cells. Chem. Commun. 53, 1626–1629. https://doi.org/10.1039/C6CC08793K
  • Pujals, S., Tao, K., Terradellas, A., Gazit, E., Albertazzi, L., 2017. Studying structure and dynamics of self-assembled peptide nanostructures using fluorescence and super resolution microscopy. Chem. Commun. 53, 7294–7297. https://doi.org/10.1039/C7CC02176C
  • Caballero, D., Blackburn, S.M., Pablo, M. de, Samitier, J., Albertazzi, L., 2017. Tumour-vessel-on-a-chip models for drug delivery. Lab Chip 17, 3760–3771. https://doi.org/10.1039/C7LC00574A

2016

  • da Silva, R.M.P., van der Zwaag, D., Albertazzi, L., Lee, S.S., Meijer, E.W., Stupp, S.I., 2016. Super-resolution microscopy reveals structural diversity in molecular exchange among peptide amphiphile nanofibres. Nat Commun 7, 11561. https://doi.org/10.1038/ncomms11561
  • De Koker, S., Cui, J., Vanparijs, N., Albertazzi, L., Grooten, J., Caruso, F., De Geest, B.G., 2016. Engineering Polymer Hydrogel Nanoparticles for Lymph Node-Targeted Delivery. Angew. Chem. Int. Ed. Engl. 55, 1334–1339. https://doi.org/10.1002/anie.201508626
  • Aloi, Antonio, Vargas Jentzsch, A., Vilanova, N., Albertazzi, L., Meijer, E.W., Voets, I.K., 2016. Imaging Nanostructures by Single-Molecule Localization Microscopy in Organic Solvents. J. Am. Chem. Soc. 138, 2953–2956. https://doi.org/10.1021/jacs.5b13585
  • van der Zwaag, D., Vanparijs, N., Wijnands, S., De Rycke, R., De Geest, B.G., Albertazzi, L., 2016. Super Resolution Imaging of Nanoparticles Cellular Uptake and Trafficking. ACS Appl. Mater. Interfaces 8, 6391–6399. https://doi.org/10.1021/acsami.6b00811
  • Aloi, A., Vilanova, N., Albertazzi, L., Voets, I.K., 2016. iPAINT: a general approach tailored to image the topology of interfaces with nanometer resolution. Nanoscale 8, 8712–8716. https://doi.org/10.1039/c6nr00445h
  • Beun, L.H., Albertazzi, L., van der Zwaag, D., de Vries, R., Cohen Stuart, M.A., 2016. Unidirectional Living Growth of Self-Assembled Protein Nanofibrils Revealed by Super-resolution Microscopy. ACS Nano 10, 4973–4980. https://doi.org/10.1021/acsnano.6b01017
  • Garzoni, M., Baker, M.B., Leenders, C.M.A., Voets, I.K., Albertazzi, L., Palmans, A.R.A., Meijer, E.W., Pavan, G.M., 2016. Effect of H-Bonding on Order Amplification in the Growth of a Supramolecular Polymer in Water. J. Am. Chem. Soc. 138, 13985–13995. https://doi.org/10.1021/jacs.6b07530

2015

  • Baker, M.B., Albertazzi, L., Voets, I.K., Leenders, C.M.A., Palmans, A.R.A., Pavan, G.M., Meijer, E.W., 2015. Consequences of chirality on the dynamics of a water-soluble supramolecular polymer. Nature Communications 6, 1–12. https://doi.org/10.1038/ncomms7234
  • de Feijter, I., Albertazzi, L., Palmans, A.R.A., Voets, I.K., 2015. Stimuli-Responsive Colloidal Assembly Driven by Surface-Grafted Supramolecular Moieties. Langmuir 31, 57–64. https://doi.org/10.1021/la5031872
  • Liu, Y., Pauloehrl, T., Presolski, S.I., Albertazzi, L., Palmans, A.R.A., Meijer, E.W., 2015. Modular Synthetic Platform for the Construction of Functional Single-Chain Polymeric Nanoparticles: From Aqueous Catalysis to Photosensitization. J. Am. Chem. Soc. 137, 13096–13105. https://doi.org/10.1021/jacs.5b08299

2014

  • Albertazzi, L., Zwaag, D. van der, Leenders, C.M.A., Fitzner, R., Hofstad, R.W. van der, Meijer, E.W., 2014. Probing Exchange Pathways in One-Dimensional Aggregates with Super-Resolution Microscopy. Science 344, 491–495. https://doi.org/10.1126/science.1250945

2013

  • Albertazzi, L., Gherardini, L., Brondi, M., Sulis Sato, S., Bifone, A., Pizzorusso, T., Ratto, G.M., Bardi, G., 2013a. In Vivo Distribution and Toxicity of PAMAM Dendrimers in the Central Nervous System Depend on Their Surface Chemistry. Mol. Pharmaceutics 10, 249–260. https://doi.org/10.1021/mp300391v
  • Albertazzi, L., Martinez-Veracoechea, F.J., Leenders, C.M.A., Voets, I.K., Frenkel, D., Meijer, E.W., 2013b. Spatiotemporal control and superselectivity in supramolecular polymers using multivalency. PNAS 110, 12203–12208. https://doi.org/10.1073/pnas.1303109110
  • Boni, A., Albertazzi, L., Innocenti, C., Gemmi, M., Bifone, A., 2013. Water Dispersal and Functionalization of Hydrophobic Iron Oxide Nanoparticles with Lipid-Modified Poly(amidoamine) Dendrimers. Langmuir 29, 10973–10979. https://doi.org/10.1021/la400791a
  • Kieltyka, R.E., Pape, A.C.H., Albertazzi, L., Nakano, Y., Bastings, M.M.C., Voets, I.K., Dankers, P.Y.W., Meijer, E.W., 2013. Mesoscale Modulation of Supramolecular Ureidopyrimidinone-Based Poly(ethylene glycol) Transient Networks in Water. J. Am. Chem. Soc. 135, 11159–11164. https://doi.org/10.1021/ja403745w
  • M. Pavan, G., Barducci, A., Albertazzi, L., Parrinello, M., 2013. Combining metadynamics simulation and experiments to characterize dendrimers in solution. Soft Matter 9, 2593–2597. https://doi.org/10.1039/C3SM27706B